DeepCool Genome III E-ATX Full Tower Case

Features:

The next evolution of liquid cooling case returns with a bold new design and cutting-edge performance. Now a full-tower chassis, GENOME III features an integrated 420mm AIO liquid cooling system, a visible reservoir, and a 5.5-inch LCD screen.

DESIGN MEETS FUTURE

Inspired by the flowing geometry of the genome, GENOME III brings a new expression to PC case design. A transparent front reservoir showcases fluid in motion, while DeepCool’s patented Z-shaped fittings route coolant tubing cleanly upward from the CPU block, enabling a hidden liquid path that keeps the interior open and unobstructed. The RGB light column synced with the motherboard adds a dynamic visual pulse, hinting at the intelligent system running within.

ALL-IN-ONE PREMIUM SOLUTION

GENOME III isn't just a case—it's a complete liquid-cooled ecosystem, ready to power your next build. Discover everything you get in this ultimate package:

Expansive Full Tower Space

Designed to comfortably house E-ATX and high-end hardware configurations, with exceptional room for upgrades and customizations.

Elite Integrated Cooling

Comes pre-equipped with a high-performance 420mm AIO cooling system, featuring DeepCool’s advanced 6th-gen PWM pump, optimized fluid pathways, and three premium fans.

Smart Data Monitoring Module

Includes a built-in vibrant LCD panel offering detailed system monitoring and effortless personalization for complete control and convenience.

INTEGRATED LIQUID COOLING SYSTEM

At its core is DeepCool’s 6th-gen PWM pump featuring a ceramic impeller, FOC control, and refined fluid channels for superior heat transfer efficiency and quiet operation. The 420mm radiator offers a larger heat exchange area than standard setups, paired with three high-performance FT14 fans for high airflow and static pressure, keeping temperatures under control even during intense workloads. An external reservoir equipped with Anti-Leak technology automatically balances internal pressure and extends system reliability for long-term operation.

SEE WHAT RUNS DEEP

The 5.5-inch LCD screen with a 480×960 resolution delivers clear, responsive monitoring that keeps essential system data in view. From processor load and GPU power to memory and storage activity, key metrics update in real time. You can also upload custom visuals—JPGs, animated GIFs, or MP4 clips—adding a personal layer to the display, all managed through the DeepCreative software.

MATCH YOUR AMBITIONS

Designed for extreme cooling, the GENOME III supports up to two 420mm radiators simultaneously or up to ten 120mm or 140mm fans for maximum airflow, ensuring stability under the most demanding workloads

Radiators:

• Side: 120/140/240/280/360/420mm
• Top: Pre-installed 420mm AIO
• Bottom: 120mm
• Rear: 120/140mm
• PSU Shrouded: 120/140/240mm

Fans:

• Side: 3×120 / 3×140mm
• Top: 3×120 / 3×140 / 2×180
• Bottom: 1×120 / 1×140mm
• Rear: 1×120 / 1×140mm
• PSU Shrouded: 2×120 / 2×140mm 

BUILT FOR THE BIG LEAGUES

The GENOME III's full-tower design offers extensive hardware compatibility, supporting EATX/SSI-ECB motherboards, GPUs up to 480mm, and air coolers up to 195mm tall. With 9 expansion slots, multiple drive bays, and supports for PSUs up to 180mm, it’s built for the most powerful configurations.

EFFORTLESS BUILDING

GENOME III features a multi-panel quick-release structure for hassle-free installation and upgrades. The partitioned cable management system, with 31.5mm of clearance, keeps routing clean and organized for a polished and efficient build

CONVENIENCE AT ARM'S REACH

Positioned near the bottom side of the case, the I/O panel keeps essential ports within easy reach for effortless device connections. It includes four USB 3.0 ports, one Audio jack, and a Gen-2 Type-C port.